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Back pain is one of the most common visits to the doctor in the United States. Worldwide, some statistics state that 4 out to 5 adults suffer from some form of back pain today. What causes back pain today can vary, but often can be isolated to some of the following conditions, including:
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Spinal stenosis
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This condition occurs when the space around the spinal cord and adjacent nerve root narrows due to arthritic bone growth and arthritis causing pressure or the pinching of a nerve(s).
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Sciatica
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This condition occurs when a herniated disk impinges on the sciatic nerve causing a severe pain that travels down the backside of the leg.
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Herniated disk
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This is when the normal contour of the outer rim of a disc, known as the annulus is disrupted, allowing cartilaginous disc material to extrude out into the spinal canal, where it can compress the nerve roots, causing sciatica-type pain.
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Spondylolisthese
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This occurs when one or multiple vertebrae in the spinal column slip forward over an adjacent vertebra.
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Spondylosis or Degenerative Disc
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This condition occurs when the disc begins to break down and deteriorate causing the upper vertebra to begin to come in contact with nerves and adjacent vertebra.
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Despite the relative success of internal fixation devices, most notably pedicle screw systems (which are fixed to the spine via screws placed through the bony pedicles of the vertebra), surgeons have long sought a less invasive method. The 1990’s saw the evolution of interbody devices that had previously only been used to span defects in the vertebra, as when entire vertebra needed to be removed for tumor (referred to as a corpectomy). Improvements in design offered the potential that these interbody devices, i.e.”cages”, could be used to fuse the spine. These cages resembled threaded screw devices that were packed with bone. The failure rate, and hence the need for revision surgery, was unfortunately unacceptable. Opinion has swung back to a combination of posterior fixation with pedicle screws and rods supplemented by interbody support. Circumferential fusions, utilizing both posterolateral (from the back and placed both left and right of the midline nerve structures) and interbody grafting, have gained in popularity. Mechanical and in vivo studies have shown the superiority of bonegrafts placed along the anterior (front) column of the spine, as in interbody fusion, especially when supplemented with pedicle screw fixation. Bonegraft heals more quickly and to a greater extent under compression. This is the case in interbody fusion, as opposed to bonegraft being placed under tension in traditional posterolateral techniques.
The major emphasis in spinal surgery at present is in how to accomplish an interbody fusion and fixation with minimal trauma to the surrounding soft tissue and nerve structures. Minimally invasive approaches put a premium on graft enhancing techniques, hence the interest in osteobiologics. This is because the effective cleaning of the bone surfaces for grafting is compromised by the limited surgical access and visualization. Minimally invasive spine surgery also demands that implants be built around the constraints of the limited access surgical field. Any reduction in soft tissue and/or bony dissection or removal, translates to less pain, complications and rehabilitation the patient will have to endure. This also brings lower overall healthcare costs overall as the patient is capable of returning to work sooner.
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